The proposed method is able to refine a prior brain volume segmentation, eliminating local patterns that are inconsistent with the brain borders. This study presents an automatic brain volume refinement (BVeR) method. Although the skull stripping procedure is time-consuming for manual assessments, most automatic approaches often present minor segmentation errors, commonly requiring a manual refinement. One of the possible data preparation steps is the skull stripping, which removes non-brain tissues from the original image. In neuroimage studies, it is usual to set a sequence of image preprocessing steps to obtain a controlled data analysis.
